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搜狐全球医讯 | 男性精液质量差,家族多种癌症风险更高

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作者 | 周亦川

编辑 | 袁月

男性精液质量差不仅影响着下一代,家人还容易得癌症?近期有研究称,患少精子症以及无精子症的男性,家族癌症风险更高。

已有多项研究显示,精液质量差与男性自身多种疾病高发相关,包括前列腺癌、结肠癌,自身免疫病及心脑血管病等。而本项《人类生殖》杂志发表的研究中,课题组收集了某生殖中心786名无精症或严重少精症男性信息,将其与五千多名正常生育的男性及其亲属信息进行对比。

来源 / unsplash

结果显示,无精症患者家族五种癌症风险显著增加,包括骨关节癌、肉瘤等软组织癌症、子宫癌、霍奇金淋巴瘤和甲状腺癌。严重少精症患者家族的结肠癌、骨关节癌及睾丸癌风险明显上升。

专家解析,不育症与癌症在遗传、环境等方面存在联系。例如,乳腺癌患者BRCA基因突变与家族成员的前列腺癌、卵巢癌等癌症高发相关,由此男性精液质量也可能与某种家族基因异常存在联系。另外,家庭成员有着相似的生活行为和环境,也与共同发病相关。

因此通过进一步探究,我们一方面可了解男性不育症的发病机制,另一方面也可评估家庭癌症风险,对两方面患者提供更优的诊疗服务。

发布于:北京市